The University of Iowa (UI, U of I, UIowa, or simply Iowa) is a public research university in Iowa City, Iowa, United States. Founded in 1847, it is the oldest university in the state. The University of Iowa is organized into 12 colleges offering more than 200 areas of study and seven professional degrees.

On an urban 1,880-acre campus on the banks of the Iowa River, the University of Iowa is classified among "R1: Doctoral Universities – Very high research activity". In fiscal year 2021, research expenditures at Iowa totaled $818 million. The university is best known for its programs in health care, law, and the fine arts, with programs ranking among the top 25 nationally in those areas. The university was the original developer of the Master of Fine Arts degree and it operates the Iowa Writers' Workshop, which has produced 17 of the university's 46 Pulitzer Prize winners. Iowa is a member of the Association of American Universities, the Universities Research Association, and the Big Ten Academic Alliance.

Among public universities in the United States, UI was the first to become coeducational and host a department of religious studies; it also opened the first coeducational medical school. The University of Iowa's 31,000 students take part in nearly 500 student organizations. Iowa's 22 varsity athletic teams, the Iowa Hawkeyes, compete in Division I of the NCAA and are members of the Big Ten Conference. The University of Iowa alumni network exceeds 250,000 graduates.